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OCR: Changes in blood tonicity are recogni ed in the osmotically sensitive cells that are sit circumventricular organs of the ante organ hypothalamus, probably the subforni amina and/or the organum vasculosum of tence of terminalis. There is evidence for the two distinct osmoreceptors: one contr ne vasopressin secretion, principally fro thirst supraoptic nucleus; the other that ser appreciation (Fig. 5.3).